Industrial symbiosis is the association of multiple firms whose waste becomes raw materials to benefit one of the other firms. These firms exist within an industrial ecosystem, which is comprised of two sections including eco-industrial parks and eco-industrial networks. When looking at the case studies of industrial symbiosis in Greece specifically, almost all of the cases at the industrial park’s spatial scale have been recorded. A more thorough look into the studies to try to zero in on the number of cases that were actively participating in industrial symbiosis and where the waste exchange was most common. Of the total cases, a very small number of them were identified at the industrial park scale. This is thought to be lower because of the decreased number of industrial parks present in the country coupled with the business and industrial industries usually not present in IPs. Still, the number of industrial parks lessens in Greece when looking at the businesses present. A little more than half of them are open and operating as the rest are under construction, haven’t been set up, or have other barriers to business. Looking at the small number of partnerships, it is clear that many can still be made with firms that are fully functional and are able to enter an agreement that can be beneficial to both sides. A large barrier to partnerships is the spacial allocation of the eco-industrial networks, distinguishing between whether the area is an industrial park or is local on the scale can be met with overlap. In fact, when looking at a distribution of spatial scales from case studies, local was six times the number of IP cases. As many times they are grouped together IP and local combined counted for the highest number of case studies in comparison to regional, national, and global. An interpretation of this provided the fact that certain types of waste are transported through the smallest spacial scales while others are saved for the larger regions. The spatial scale and all that it encompasses are very important to look out for and consider when studying industrial symbiosis. Barriers to partnerships of firms are factors as to why there are a low number of relationships between companies that could be beneficial. New developments with eco-industrial networks need to be explored as well as a deeper dive into the specific conditions that surround the industrial park’s spatial scale.